Sage is a plant that is found wild in Mediterranean Europe from sea level to mountain areas, preferably in dry land and unproductive. Widely used throughout history for its medicinal properties, but also culinary and aromatic, it began to be used more recently as an ornamental plant in gardens. This combination of culinary, essential and medicinal uses of plants like sage always emerges from a conscious study of them: for this we must observe, describe the most relevant properties and put all that data written with the intention that this study can be known by the maximum number of people. This diffusion of botanical knowledge was conducted in classical times by authors such as Dioscorides, whose text was known in al-Andalus through Córdoba; people from al-Andalus like the Sevillian Ibn-al Awwam actually recovered and translated these texts to assist in the dissemination of knowledge and revived classical botanical science. Already in modern times, during the European Renaissance in the sixteenth century, when Seville was the door of America, new species came to the city from the New World, doctors and pharmacists as Monardes or Tovar took up this classic tradition recovered by the Andalusian of studying the properties of plants and record the results of their observations. There is thus a line connecting through time to the classics with the Seville humanistic physicians of the 16th century, a line that is maintained at its center by the al-Andalus period. A line, ultimately, of botanical knowledge transmission.