In their tree variant, the angel’s trumpet was already known by the Spaniards during the seventeenth century. It is also known by the generic name of datura, alluding to a type of drug that is extracted from various plants of the genus. From brugmansia a wine of datura was extracted that was used by some Indians of the Peruvian region to cause violent states of arousal. Four lithographs are dedicated to it with the name datura arborea in the work of the priest and scientist José Celestino Mutis from Cadiz (1732-1808), promoter of the Royal Botanical Expedition of the New Kingdom of Granada that began in 1783 and continued until 1816, even after Mutis death. This expedition was responsible for botanical research and the development of a herbarium of those territories that now comprise the current northern Peru and Brazil and much of Panama, Ecuador, Venezuela and especially Colombia. Mutis, who studied in Cadiz and Seville, was one of the most notable naturalists who of the Spanish eighteenth century. Proof of this is the private correspondence with the botanical master at the time, Carolus Linnaeus or with Von Humboldt.